Bioperine is a convenient and concentrated form of black pepper’s ingredient called piperine. Bioperine enhances bioavailability and absorption. Bioperine is a safe and pure nutritional piperine supplement. This is an alkaloid that is available from the fruits. Piperine is responsible for the ability of pepper to enhance the nutrients bioavailability. 95% piperine is present in Bioperine. Black pepper was popular as it was the most desired spice. The black pepper was useful in ayurvedic medicine as it increased the food digestibility. The pepper consumption shows positive indication by generating internal heat. The nutritional status is based on a person and his eating style. Bioperine enhances the heat production in the body and this result in food digestion and eventually the energy is used. Bioperine facilitates the bioavailability of nutrients in a broad range. Bioperine is considered to be a thermogenic local agent as it increases the thermogenic reactions. Bioperine is an apposite nutritional supplement identical to pepper that is to food.

Green Tea Extract- By increasing the body's metabolism, it is widely believed that green tea extract largely aids in weight loss.

Hoodia Gordonii, which although popular, has no published randomized controlled trials in humans to show hoodia is safe or effective in pill form. One study published in the September 2004 issue of Brain Research found that injections of p57 (The Active ingredient in Raw, Fresh Cut Hoodia, not dried) into the appetite center of rat brains resulted in altered levels of ATP, an energy molecule that may affect hunger. The animals receiving the P57 injections also ate less than rats that received placebo injections. However, this was an animal study and INJECTIONS IN THE BRAIN are very different from oral consumption, so it cannot be used to show that oral hoodia can suppress appetite in humans. Hoodia Gordonii is a succulent (a cactus of the aloe family) found in the Kalahari desert of South Africa. Most Hoodia Gordonii products contain very little, if any of the active ingredient needed to suppress hunger. Real Hoodia is very rare and is even an endangered plant. Most importantly, Hoodia has only demonstrated any effect in fresh, raw pieces of the plant. The effectiveness of powdered Hoodia has yet to be shown and may actually increase hunger. It's main use is as a cheap alternative to the more expensive weight loss herbs, which are the only alternative left after the banning of ephedra. Most supplement manufacturers can not use the more expensive weight loss herbs because it will result in a product that would be too expensive to compete with other more popular inexpensive diet supplements.

Theobromine- The bitter alkaloid found in chocolate is known as theobromine. It comes from the cacoa plant and is found in chocolate as well as chocolate free foods that are consist of theobromine. Theobromine belongs to the methylxanthine class of chemical compounds. It is found in the leaves of the tea plant, the kola or cola nut and acai berries. No bromine is present in theobromine, despite the name. The properties of theobromine are that it is souluble in water, is crystalline, is a bitter powder, is listed as white or colorless in color. It is considered a lesser homologue because it has a lesser effect to caffeine. Theobromine is the kind of isomer which belongs to paraxanthine and theophylline at the same time. It is basically a xanthine having two methyl groups.