Caffeine is the most widely used legal stimulant of the central nervous system and is also used in Designer Supplements Adrenalean, with characteristics that have been described as restoration of alertness and removing from drowsiness. Coffee, Tea, many soft drinks and energy drinks as well as nutrition supplements have this ingredient, which is a psychoactive substance, a xanthine alkaloid that can act as a adenosine receptor antagonist, as well as a phosphodiesterase inhibitor. Although regular use of caffeine seems to have nootropic effects, enhancing cognitive abilities, it also is known to provide long term effects on the nervous and cardiovascular system, like in one study it was proven that people with normal to low blood pressure have the possibility of developing a heart disease significantly reduced, as well as the chance of getting the Parkinson’s disease.

Evodiamine, a bioactive alkaloid extract from the Evodiae Fructus plant, sometimes called Wu-Chu-Yu. Evodiamine is related to capsaicin, found in cayenne pepper. Evodiamine is a vanilloid receptor agonist, and may enhance lipolytic activity. Evodiamine has been shown to raise the body’s skin temperature and decrease core temperature, which is thought to burn calories and fat for energy.

Hordenine has antibacterial and antibiotic properties and is another weight loss agent that also stimulates the central nervous system.

L-Huperzine A is extracted from a Chinese herb called Huperzia Serrata. L-Huperzine A inhibits the breakdown of Acetylcholinesterase that aids in raising the level of Acetylcholine, a memory neurotransmitter. It also helps in strengthening the brain’s NMDA receptors (N-methyl D-aspartate) that enhances the communication between the brain cells resulting to enhanced concentration, focus, learning and other brain functions. L-Huperzine A also stimulates the synthesis of nerve growth factor that is responsible for maintaining and promoting youthful and healthy brain function. L-Huperzine A quickly and potently boosts the memory, learning and the concentration functions of the brain for a short period of time.

Methylaricaiden is an alkaloid that may be obtained from betel nut, the fruit of a palm tree. It is known to be a potent stimulant that improves the alertness, focus and concentration. It enhances the mood, and fights depression. It is also a mild laxative that helps prevent water retention, cleans the body, and aids in weight loss. It alleviates the symptoms of rheumatism and arthritis. It also helps treat headaches and fever. Methylarecaiden has prevents and kills parasites in the body. It also promotes wound healing. It also has antioxidant properties that scavenges free radicals and prevent it from causing cell damage.

Phenylethlamine HCL is a salt of phenylethylamine. It is a crystalline solid and is formed by treating phenylethylamine with HCl. Its IUPAC name is 2 phenylethylamine HCl. The scientific name elucidates its chemical structure. It is an aromatic compound meaning that it has a basic benzene ring. It further has a two carbon chain attached at position 2 of the ring and the chain terminates in an amino group. It occurs naturally in some foods like chocolates but the food item might get metabolized too quickly sometimes for it to have a significant effect on the body. This substance has quite profound effects on the level of dopamine in the central nervous system, provided it passes the blood brain barrier. It increases dopamine level and at the same time inhibits dopamine transmitters resulting in a buildup of dopamine in the brain. While excessive levels of dopamine in the CNS are not healthy, the neurotransmitter does regulate cognition, mood, voluntary movement and other brain functions.

Quercetin, a bioflavonoid derived mostly from blue-green algae. Quercetin is a strong antioxidant commonly found in onions, wine and tea.

Synephrine HCL is a stimulant that bares close similarities to caffeine, it aids in increasing metabolic rate as well as burning excess calories.