Senna Leaf is used as laxative since many centuries. Senna Leaf is a peelable bark that is found in the upper Nile regions. Senna was in use by the early Egyptian physicians more than 3500 years and was prescribed to distinguished patients. American Indians as well used the American Senna as it had the combination of many aromatic herbs. This leaf is recommended against acute constipation as it is useful in emptying the bowels prior to X-rays. Prior to any abdominal operations this leaf is recommended. This leaf is also useful for disorders relating to soft stool such as hemorrhoids, anal fissures and other rectal operations. Senna leaf is used in brewing tea and is also used as decoction. This leaf as active glycosides and has excellent therapeutic benefits such as antispasmodic, antiseptic, antiulcer and cathartic. These leaves stimulate cellular regeneration and are good for detoxification as well as cleansing.