Bioperine is derived from the extract of Piper nigrum L (black pepper) or Piper longum L (long pepper). Bioperine activates the thermogenesis process that generates energy at the cellular level. This process also helps in burning of fats. It also increases the absorption of nutrients and vitamins. It ensures that the body benefits and is able to efficiently use the nutrients from the food. It also boosts the metabolism that makes it effective in weight loss and maintenance. Because of the boost in metabolism, it also provides the body an increased supply of energy. It also aids in the proper digestion.

Citric Acid is found in several citrus fruits, including pineapples, limes, gooseberries, plums, peaches, lemons, grapefruit, and oranges. It assists in preventing urinary tract infections. It is also applied as a natural preservative in lieu of chemicals. It helps energy production within the cells. It is a good natural astringent and regulates pH in digestive tract. Citric acid boosts efficient digestive function and helps remove toxins from body. It provides prevention against diarrhea, dysentery, and other bowel diseases. Citric acid assists in breakdown of fatty foods and increasing appetite. It helps eliminate fatigue. Citric acid in a little modified form, potassium citrate, can halt human heartbeat for greater facility during surgery and also is used to leach damaging metals from soil in landfills.

Cyclic Adenosine Monophosphate 3'-5'-cyclic adenosine monophosphate or Cyclic Adenosine Monophosphate, a second messenger that mediates the action of several eptide or amine hormones, is abbreviated as cyclic AMP or cAMP. cAMP is thus vital for varied biological processes and used for intracellular signal transduction in various organisms. This major communicator is a result of the action of the enzyme adenyl cyclase on ATP. As such, cyclic AMP performs many physiological functions and is also responsible for increasing blood glucose levels. Adrenaline that enhances blood sugar levels in the body is able to do so by stimulating cAMP production. Cyclic AMP plays an important role in the following: urine regulation synthesis of flagellar proteins in bacteria hormone release sensory and nerve processes Apart from these functions, it also helps in breakdown of lipids in some organisms to produce energy in the absence of sufficient glucose.

Dioscorea Villosa extract is a medicinal herb commonly knows as the wild yam. It has medicinal properties that help in curing the pain caused during menstrual cycle, stomach cramps, and discomfort from gallstones and rheumatoid arthritis. It has been used fro centuries by the Native Americans. It is also used by herbalists for female and childbirth related problems. Along with herbal medicine, this plant is of great use in the modern medicine as well. It is because of this plant that birth control pills are so commonly and easily available. Its steroid like property explains the vast usage of this plant for medicinal purposes. But consumption of this extract may also lead to a number of side effects. Vomiting, diarrhea, nausea and headache are some of the most common side effects of dioscorea villosa extract.

Evodiamine has been used in Chinese medicine and by Chinese herbalists for centuries for weight loss purposes. It is an extract from a plant, Evodia or Tetradium, actually a tree genus of the family Rutaceae. The bee bee tree, as it is called besides Euodia and Evodia, provide a bioactive alkaloid that the Chinese have nicknamed Wu-Chu-Yu. This extract not only can interact with UCP1, a thermogenic protein, which as a consequence burns energy as heat, but also has shown in studies on mice to reduce the fat uptake. Evodiamine seems to increase the resting temperature of humans, whereby increased fat and calories are burned in order to supply the heat. Deemed a breakthrough in thermogenesis, evodiamine is subject of several clinical studies.

Glabra, commonly known as licorice, is a root used to extract a sweet flavor from. Licorice is a plant belonging to the legume family, like peas and beans. It takes two to three years after planting for licorice to be harvested in autumn. It requires deep, fertile, well drained soil with a lot of sun to be able to grow. The extract from licorice is produced by boiling the roots with water and then evaporating all the water. This extract is then sold both in the form of solid and liquid. Glabra consists of a sweetener called glycyrrhizin which is many times sweeter than sucrose. It is used in lot cough syrups and in ayurvedic medicine. Candies made from licorice roots are famous all over the world. Hence it is in many pharmaceutical and confectionery products.

Guggulsterone is a plant sterol found in the resin of the guggul plant, Commiphora mukul. It acts as an antagonist of the farnesoid X receptor, which was earlier believed to result in decreased cholesterol synthesis in the liver.

L-Tyrosine is a common amino acid and a para-isomer of tyrosine. It is deemed organic because of the carbon atom present and it is nonessential to survival, but works as a building block of protein. It is also viewed as a precursor of dopamine, which has several effects, like offsetting fatigue, mental and physical, as well as increasing the impression of well being. When the amino acid phenylalanine is broken down, L-Tyrosine can be won completely naturally. Besides being a precursor of the aforementioned neurotransmitter dopamine, L-Tyrosine is also deemed a precursor to some adrenal hormones, namely epinephrine and norepinephrine. In body building circles this supplement is popular to offset fatigue after a hard training or competition, but also to raise mental alertness while working out.

Octopamine is a biogenic substance which is containing an amine group, apparently related to noradrenaline, which is a catecholamine functioning as both, neurotransmitter and a hormone. Similar to norepinephrine, which is another name for noradrenaline, octopamine may act as a stress hormone, triggering increased heart rate, energy consumption and blood flow, even the blood pressure. One side effect of octopamine is apparently the release of fat from the adipocytes, which are the fat cells where excess energy is being stored. This side effect prompted the use of octopamine as a dietary supplement aimed at weight loss, but used in combination with other stimulants. Octopamine has been discovered in the middle of the twentieth century, but the use as a fat removal agent is very recent.

Phosphatidylcholine has a role in membrane mediated cell signaling and is currently being experimented on weight loss treatments.

Phosphollipid complex is formed by the combination of lipids and phosphate. They are grouped into three categories. 1. Glycerophosphates- Glycerophosphates are one of the important factors for cell membranes. They are also responsible for intracellular messaging and act as a hormone stimulant. 2 Sphingophosphatides- These phospholipids are responsible for transportation of water and fat soluble materials through cell membranes. It also helps to stabilize water soluble compounds. 3. Glycolipids. They help to maintain the structure of the cell membrane by attaching themselves with other components. Phospholipids complex is important for maintaining physiological activity of the body as they are an important factor for bonding and formation of enzymes, amino acids, etc.

Quercetin is a flavanoid derived from plants and is widely used as a nutritional supplement. There are many studies which are being conducted to exactly determine the benefits of Quercetin. It is said to have antioxidant and anti-inflammatory properties and hence is being tested to help curb and cure terminal diseases like cancer. The high intake of fruits and vegetables is good for cancer treatments. Many researchers believe that these qualities of Quercetin are what allow it to be used for treating cancer as well. Quercetin is classified into the IARC group 3; which categorizes food and drugs as that which are not carcinogenic.

Rhodiola Rosea Extract is the extract of a plant that grows in the cold regions of the world from the Crassulaceae family. It is considered to be dioecious, which is having both male and female parts. Rhodiola Rosea is an adaptogen and that is a natural herbal medicine that increases the body’s resistance to trauma, stress, fatigue, and anxiety. It improves the mood and can lessen the effects of depression. This extract supports the nervous system and helps to significantly boost mental functions by increasing blood supply to the brain. It can also normalize the heart rate after intense exertion. Combined with moderate exercise it can aid in significant weight loss because it activates hormone-sensitive lipase, which enables the breakdown of fat stored in adipole tissue. Fat stored in adipole tissue is normally very difficult to get rid of.

Ribonucleic Acid , abbreviated RNA, is very similar to DNA with some important differences in structure. It is single-stranded instead of double-stranded, contains ribose instead of deoxyribose, and has a base of uracil instead of a base of thymine as DNA does. RNA is a molecule that consists of a long chain of nucleotide units and those units consist of a nitrogenous base, a ribose sugar, and a phosphate. It is transcribed from DNA by enzymes called RNA polymerases and it is essential to protein synthesis. Ribonucleic Acid conveys genetic information and catalyzes important biochemical reactions.

Smilax is actually a genus that contains over three hundred species, mainly found in sub-tropical and tropical areas throughout the world. These are climbing plants, many of which have flowers and bear some kind of fruit. Many smilax plants have found uses in medicine, some for symptom remedy of the premenstrual syndrome; some others for treatments of hormonal imbalance induced or aggravated skin diseases. Many smilax plants are being used in local cuisines, either for herbal drinks or for sweet snacks; moreover, a Chinese variant has a long history as treatment against syphilis. Smilax officinalis has found use with body building circles as sarsaparilla root, where the plant’s sterols seem to influence human’s metabolic processes. The belief of many herbalists is that S. officinalis is making the body produce more testosterone.

Taraxacum Officinale, also called dandelion, has been traditionally used in herbal medicines. It can also be effective in treatment of kidney disorders, heartburn and indigestion. It can be beneficial in treating liver disease and can also be used in association with other medicines in treatment of upper respiratory tract infections, including bronchitis and pneumonia, and hepatitis. It is helpful in treatment of appetite loss and fluid retention. It is a good source of the nutrient lecithin that increases brain’s acetylcholine, a substance helpful in maintaining brain function and that can also be beneficial in slowing or even stopping progression of Alzheimer’s disease. Lecithin also helps the body maintain proper liver function.

Trimeylxanthine Anyhydrous is a form of caffeine that is found in many energy supplements. This stimulant is very beneficial for those who are looking to increase their energy and stamina levels. Trimelyxanthine anyhydrous is often combined with other ingredients to create various proprietary blends that are sold as weight loss supplements or energy supplements. Trimelyxanthine anyhydrous may also be marketed as a supplement that will bring about greater mental clarity, mental alertness, and focus. You can find this stimulant in both pill form and more potent powder form, although not generally sold alone but found as an active ingredient in other products.

Vinpocetine is a compound that is derived from a substance found in the leaves naturally called vincamine. Vinpocetine was established in 1960s. This was available in Japan and Europe with prescription and in Canada and the United States it was available in health food stores as well as online as dietary supplement. Vinpocetine increases the blood circulation and reduces the impairment in the brain. Vinpocetine is given to people suffering with Alzheimer’s disease as a complementary treatment. It enhances the use of oxygen in the brain and protects the brain cell from damage. Thereby it works in enhancing the blood flow towards the brain. Vinpocetine prevents strokes and memory disturbances. Vinpocetine is useful in improving, hearing, eyesight and also in alleviating problems that are connected to menopause. Vinpocetine has effect on the damaged areas in the brain and is also an anti-oxidant. So it shields the brain from aging. The dosage recommended is 5mg tablet twice or thrice daily.

Vitamin B3 is also known as Niacin or nicotinic acid. It helps in the conversion of carbohydrates into glucose that serves as fuel for energy. It also helps the body in metabolizing fats and proteins. Niacin also helps in the production of hormones necessary for the body to function properly. It is also effective in improving the circulation in the body. It lowers cholesterol, triglycerides and blood sugar level. It also helps in the treatment of coronary artery disease. It also helps in regulating the blood sugar level. Niacin also helps prevent the Pellagra disease, which causes digestive problems, diarrhea, dermatitis, hyper-pigmentation, amnesia, dementia, delirium, and even death. Niacin also helps prevent Alzheimer’s disease, diabetes, and is also effective in treating acne.