Bioperine is an extract from the fruit of Piper nigrum L (black pepper) or Piper longum L (long pepper) that contains 95 percent of piperine. Black pepper is a common household spice. Extract from black pepper has also been used extensively as a medicine. To reach the greatest quality during the harvest, the pepper is reaped before ripening and after that is placed to dry under the sun rays. Bioperine is known for its effect to enhance the efficiency of many supplement nutrients. Bioperine acts to enhance the body’s natural therogenic activity – giving the name thermonutrient. This enhancement brings about increased metabolic rate creating demand for supple of many nutrients such as vitamins, minerals, herbals, amino acids. It sets in motion a process that brings about better digestion and faster gastrointestinal absorption.

Citric Acid is found in several citrus fruits, including pineapples, limes, gooseberries, plums, peaches, lemons, grapefruit, and oranges. It assists in preventing urinary tract infections. It is also applied as a natural preservative in lieu of chemicals. It helps energy production within the cells. It is a good natural astringent and regulates pH in digestive tract. Citric acid boosts efficient digestive function and helps remove toxins from body. It provides prevention against diarrhea, dysentery, and other bowel diseases. Citric acid assists in breakdown of fatty foods and increasing appetite. It helps eliminate fatigue. Citric acid in a little modified form, potassium citrate, can halt human heartbeat for greater facility during surgery and also is used to leach damaging metals from soil in landfills.

Cyclic Adenosine Monophosphate 3'-5'-cyclic adenosine monophosphate or Cyclic Adenosine Monophosphate, a second messenger that mediates the action of several eptide or amine hormones, is abbreviated as cyclic AMP or cAMP. cAMP is thus vital for varied biological processes and used for intracellular signal transduction in various organisms. This major communicator is a result of the action of the enzyme adenyl cyclase on ATP. As such, cyclic AMP performs many physiological functions and is also responsible for increasing blood glucose levels. Adrenaline that enhances blood sugar levels in the body is able to do so by stimulating cAMP production. Cyclic AMP plays an important role in the following: urine regulation synthesis of flagellar proteins in bacteria hormone release sensory and nerve processes Apart from these functions, it also helps in breakdown of lipids in some organisms to produce energy in the absence of sufficient glucose.

Dioscorea Villosa extract is a medicinal herb commonly knows as the wild yam. It has medicinal properties that help in curing the pain caused during menstrual cycle, stomach cramps, and discomfort from gallstones and rheumatoid arthritis. It has been used fro centuries by the Native Americans. It is also used by herbalists for female and childbirth related problems. Along with herbal medicine, this plant is of great use in the modern medicine as well. It is because of this plant that birth control pills are so commonly and easily available. Its steroid like property explains the vast usage of this plant for medicinal purposes. But consumption of this extract may also lead to a number of side effects. Vomiting, diarrhea, nausea and headache are some of the most common side effects of dioscorea villosa extract.

Evodiamine has been used in Chinese medicine and by Chinese herbalists for centuries for weight loss purposes. It is an extract from a plant, Evodia or Tetradium, actually a tree genus of the family Rutaceae. The bee bee tree, as it is called besides Euodia and Evodia, provide a bioactive alkaloid that the Chinese have nicknamed Wu-Chu-Yu. This extract not only can interact with UCP1, a thermogenic protein, which as a consequence burns energy as heat, but also has shown in studies on mice to reduce the fat uptake. Evodiamine seems to increase the resting temperature of humans, whereby increased fat and calories are burned in order to supply the heat. Deemed a breakthrough in thermogenesis, evodiamine is subject of several clinical studies.

Glabra, commonly known as licorice, is a root used to extract a sweet flavor from. Licorice is a plant belonging to the legume family, like peas and beans. It takes two to three years after planting for licorice to be harvested in autumn. It requires deep, fertile, well drained soil with a lot of sun to be able to grow. The extract from licorice is produced by boiling the roots with water and then evaporating all the water. This extract is then sold both in the form of solid and liquid. Glabra consists of a sweetener called glycyrrhizin which is many times sweeter than sucrose. It is used in lot cough syrups and in ayurvedic medicine. Candies made from licorice roots are famous all over the world. Hence it is in many pharmaceutical and confectionery products.

Guggulsterone- Commiphora wightii, or the so called Guggul tree is a flowering shrub or rather a small tree which can grow up to a size of 4 meters. Once very common in India, it is now there listed as endangered, but not in northern Africa or elsewhere in central Asia. It was very popular in the Indian Ayurvedic medicine, but also currently in the western medicine for treating of heart problems. The hydrocarbon secretion of Guggul contains a plant sterol, guggulsterone, which in the human body seems to act as an antagonist to the farnesoid X receptor. Furthermore, guggulsterone is active in increasing the natural thyroid production. This in turn stimulates the metabolism and may raise the body temperature, burning stored excess fat.

L-Tyrosine is a non essential amino acid occurring in the body. L-Tyrosine may be created from the synthesis of phenylalanine which is also an amino acid. It is one of the building blocks of proteins in the body. It is also a precursor for several neurotransmitters such as L-dopa, dopamine, epinephrine and norepinephrine. It helps treat and prevent illness such as Parkinson’s disease, Alzheimer’s disease, depression and other such mood disorders. It also helps protect the body from free radical damages. It also helps protect the skin from UV rays damages on the skin by aiding in the production of melanin. It also helps in increasing the metabolic rate that speeds up muscle building and fat loss. It also increases the endurance.

Octopamine, which is a trace amine, recently believed to be a lipotropic for fat loss. Octopamine has low oral bioavailability and is readily broken down by MAOI, as well as metabolized by the gut wall, which may mean it would not work well when taken orally, but more research is needed to prove its positive or negative effects.

Phosphatidylcholine is used for treating anxiety, eczema, gallbladder disease, hepatitis, manic-depressive illness, peripheral vascular disorders, hyperlipidemia, improving ultrafiltration in peritoneal dialysis, tardive dyskinesia, premenstrual syndrome, memory loss, Alzheimer's disease, immunodepression, and preventing aging. Intravenously, phosphatidylcholine is used for angina, lipid atheromas, fat embolism, ypercholesterolemia, liver disease, and fatty plaque deposits. Subcutaneously, phosphatidylcholine is used for lipoma, periorbital fat pad herniation, xanthelasmas, and removing fatty deposits for cosmetic purposes.

Phosphollipid complex is formed by the combination of lipids and phosphate. They are grouped into three categories. 1. Glycerophosphates- Glycerophosphates are one of the important factors for cell membranes. They are also responsible for intracellular messaging and act as a hormone stimulant. 2 Sphingophosphatides- These phospholipids are responsible for transportation of water and fat soluble materials through cell membranes. It also helps to stabilize water soluble compounds. 3. Glycolipids. They help to maintain the structure of the cell membrane by attaching themselves with other components. Phospholipids complex is important for maintaining physiological activity of the body as they are an important factor for bonding and formation of enzymes, amino acids, etc.

Quercetin is a flavanoid derived from plants and is widely used as a nutritional supplement. There are many studies which are being conducted to exactly determine the benefits of Quercetin. It is said to have antioxidant and anti-inflammatory properties and hence is being tested to help curb and cure terminal diseases like cancer. The high intake of fruits and vegetables is good for cancer treatments. Many researchers believe that these qualities of Quercetin are what allow it to be used for treating cancer as well. Quercetin is classified into the IARC group 3; which categorizes food and drugs as that which are not carcinogenic.

Rhodiola Rosea Extract can help increase resistance against fatigue and can reduce stress. Classified as adaptogens among the herbs, it prevents different harmful impacts caused by physical and mental stress and illness. Rhodiola Rosea is particularly helpful for athletes because of its adaptogenic properties and its capability to enhance efficiency of mitochondrial respiration in skeletal muscle. It also improves mental work capacity and resists mental fatigue. Research has found that it helps protect against cancer. It can also be beneficial for people who suffer from high altitude sickness. Its intake can better endurance exercise capacity in young people and may also benefit people suffering from certain kinds of glucose level and cardiac conditions. Rhodiola Rosea Extract helps prevent ischemic brain damage development.

Ribonucleic Acid - Derived from yeast, Ribonucleic Acid (RNA) is an antioxidant and plays a vital role in protein synthesis, and other chemical activities of cells. It passes genetic information from DNA to proteins made by the cells. It enhances the capability to learn. RNA also helps treat Alzheimer’s disease and depression, and increases energy levels. It tightens the skin, enhances sex drive and helps in countering aging effects. It is also helpful in recovery after surgical procedures and helps boost immune system response. It assists in improving prognosis of burn victims. A supplement containing RNA can reduce the incidence of peri-operative infections and improve healing of wound. It can also be helpful in epilepsy.

Smilax is actually a genus that contains over three hundred species, mainly found in sub-tropical and tropical areas throughout the world. These are climbing plants, many of which have flowers and bear some kind of fruit. Many smilax plants have found uses in medicine, some for symptom remedy of the premenstrual syndrome; some others for treatments of hormonal imbalance induced or aggravated skin diseases. Many smilax plants are being used in local cuisines, either for herbal drinks or for sweet snacks; moreover, a Chinese variant has a long history as treatment against syphilis. Smilax officinalis has found use with body building circles as sarsaparilla root, where the plant’s sterols seem to influence human’s metabolic processes. The belief of many herbalists is that S. officinalis is making the body produce more testosterone.

Taraxacum Officinale is the most common weed flowering plant found worldwide. The two most common species are Taraxacum officinale and Taraxacum erythrospermum, also known as the dandelion flower and the dandelion parachute ball. A flower head of such a dandelion flower is structured out of hundreds of smaller florets. These biennial or perennial herbaceous plants are native to Europe, the Northern Hemisphere. It has been found out that the flowers of dandelion contain a strong antioxidant, luteolin, which is a flavonoid with diverse properties, such as inflammation inhibitor, immune system modulator and a carbohydrate metabolism promoter. Chinese medicine has used this plant for centuries for medicinal purposes, usually in form of a tea concoction, applied as a liver detoxifying method. Other uses were listed as inflammation reduction and as a diuretic.

Trimeylxanthine Anyhydrous is a form of caffeine that is found in many energy supplements. This stimulant is very beneficial for those who are looking to increase their energy and stamina levels. Trimelyxanthine anyhydrous is often combined with other ingredients to create various proprietary blends that are sold as weight loss supplements or energy supplements. Trimelyxanthine anyhydrous may also be marketed as a supplement that will bring about greater mental clarity, mental alertness, and focus. You can find this stimulant in both pill form and more potent powder form, although not generally sold alone but found as an active ingredient in other products.

Vinpocetine, a memory enhancer. Vinpocetine makes cerebral microcirculation (blood flow) easier, increases brain cell ATP production, and increases useability of glucose and oxygen.

Vitamin B3, commonly called Niacin, exists in two main forms, niacin and niacinamide. The niacin form produces a flushing and itching of the skin when taken at higher dosages and this feeling is only temporary.